120 14th Street Orange Grove
Linksfield Johannesburg
2192
reception@linksfieldoncology.co.za
010 142 4760
Targeted Therapies
Targeted therapy represents a revolutionary approach in cancer treatment, focusing
on specific molecules and pathways involved in cancer growth and progression. We offer advanced targeted therapies designed to precisely target cancer cells while
minimising damage to healthy tissue, providing new hope and effective treatment
options. How Targeted Therapy Works:
Targeted therapies work by identifying and attacking specific proteins or genes that
contribute to the growth and survival of cancer cells. Unlike traditional chemotherapy,
which affects all rapidly dividing cells, targeted therapies are tailored to block the
actions of cancer-causing molecules or pathways. This precision helps to inhibit
cancer cell growth, promote apoptosis (cell death) and shrink tumours.
Types of Targeted Therapies:
1. Monoclonal Antibodies: These are laboratory-produced molecules designed to bind to specific targets on cancer cells, marking them for destruction by the immune system or blocking their ability to grow.
2. Tyrosine Kinase Inhibitors (TKIs): These drugs block signals that promote the growth of cancer cells, often used in cancers driven by abnormal protein kinases, such as EGFR or ALK inhibitors in lung cancer.
3. Angiogenesis Inhibitors: These medications block the formation of new blood vessels that tumours need to grow, often used in cancers like renal cell carcinoma and certain types of breast cancer.
4. PARP Inhibitors: These drugs interfere with the ability of cancer cells to repair DNA damage, particularly effective in cancers with BRCA mutations, such as ovarian and breast cancers.
We are committed to providing compassionate, patient-centred care with the latest
advancements in targeted therapies.
Our practice is built on a foundation of empathy, understanding and a commitment to delivering outstanding medical care.